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Automated library construction vs manual operation in reproduction? Take a look at the on-site picture

Release date:2019-10-10Writer:MGIViews:2649Share

In recent years, with the promotion of high-throughput sequencing in the field of reproductive health, the number of clinical samples has been increasing, and the laboratory's requirements for sample processing quality have also increased. The traditional manual construction of the library has been unable to meet the needs of the construction of the new situation. How to solve the increasingly urgent problem of library construction in the field of reproductive health? MGI gave its own answer.


High-throughput sequencing in three major applications in the field of reproductive health


What are the advantages of automated library construction compared to manual one? We used the MGISP-100 automated sample preparation system to conduct a competition:

                                          

Five advantages: sample preparation automation helps clinical promotion of reproductive detection

Automation

Manual operation

Unattended, less fragmented time

More free time for experimenter

Frequent manual intervention

Need people online all the time

Processing in batches

The throughput is greatly improved

Single operation

Low throughput and slow speed

Standardization of the library construction process and stable production process;

Convenient to copy in different labs

It is difficult to standardize and is affected by the professional level, training level and quality of the personnel.

Easy to get started,

Can be mastered in two days

High professional quality and long training period

One machine for multi-purposes, one person can operate multi-machines

Significantly reduce labor costs

Different processes need to invest more manpower to increase throughput.

In order to meet the needs of different application scenarios, MGI has introduced two automated sample preparation systems, MGISP-100 and MGISP-960.


(Note: MGISP-100 is the world's first automated library construction equipment that has obtained China's NMPA medical device certificate of Class II)


Clinical application case


Customer A: customer from a Level III hospital


Situation of usage:

At the same time, three kinds of fertility tests such as NIPT, PGS and CNV were carried out, and the weekly throughput was 96 cases.

Laboratory configuration:

1 MGISP-100 with 1 basic operator.

Customer Reviews:

"MGISP-100 can realize a variety of uses on one machine. It's easy to operate, and can be used after 2 days of simple training so that we can give more time on clinical research."


Customer B: customer from a large medical laboratory


Situation of usage:

The NIPT test was carried out, and the daily throughput was about 300-600 samples.

Laboratory configuration:

3 MGISP-960 with 1 machine operator and 1 reagent preparer.

Customer Reviews:

"MGISP-960 has greatly reduced personnel input and increased daily throughput, providing us with high productivity and we no longer need to worry about the failure rate of constructing a library."


We have seen that the laboratory has achieved significant improvements in sample throughput, standardization, and economics with the use of MGI's series of automated library construction equipment. In the future, high-throughput sequencing technology will be widely used in the field of reproductive field. Automated sample preparation systems will also be further popularized.


video link:

https://mp.weixin.qq.com/s/6OPz5XN4fDzY97nH9ZZ_9A

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