Case 2 Human totipotent stem cell

Using DNBelab C4 and DNBSEQ sequencing platforms, single-cell transcriptome (scRNA-seq) and chromatin accessibility (scATAC-seq) sequencing was performed on 8CLC-induced cell samples, and the characteristics of the 8CLC population were analyzed in detail, and in multiple The four induction time points delineate the dynamic changes of transcriptome and chromatin opening during 8CLC induction, providing an important platform and resource for studying zygotic genome activation and developmental regulation at the human 8-cell stage.