Unleash your ultimate sequencing speed
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Unleash your ultimate sequencing speed

As one of the sequencers with the fastest speed among mid-low throughput in the world, DNBSEQ-G99(1) is developed based on MGI’s core DNBSEQ sequencing technology, enabled by innovations in biochemistry, optics, fluidics, temperature control, and other core systems. DNBSEQ-G99 is especially applicable for multiple sequencing methods, it only needs 12 hours to finish PE150 sequencing.

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8~48GB per run                                

Only 12 hrs for PE150 (from loading to FASTQ)                                       

Supports multiple read lengths, including PE50, SE100, PE150                               
Applicable to multiple sequencing methods

Performance Parameter

Maximum number of Flow cells  

Lanes/Flow cell

Effective Reads*/Flow Cell

Supported Reads Lengths*** Data Output Q30**

Run Time





8-16 G >90% 5h


24-48 G

>85% 12h
APP-C SE100 8-16 G >90% 5h
APP-C PE150 24-48 G >85% 12h
* The effective reads are based on the sequencing of an internal standard library. Actual output may vary depending on sample type and library preparation method.
** The percentage of bases above Q30 is the average of an internal standard library over the entire run. Actual performance is affected by factors such as sample type, library quality, and insert fragment length.
*** DNBSEQ-G99 also supports SE50 and PE100 sequencing, and the existing kits can support SE50, PE100 read length sequencing.
SE400 and PE300 will be released on Q2 2023.
Method Application

Recommended read length

Data size Sample per Run

1 flow cell

2 flow cells

Targeted Capture/

Multiplex PCR

Oncology panel


Small panel: ~1Gb/Sample

24 48
Genetic disease diagnosis (small panel) PE150

Thalassemia: ~0.2M/Sample

Deafiness: ~5Gb/Sample

4 8

ATOPlex panel

PE100, PE150

Respiratory tract panel: 5M/Sample

COVID-19 panel: 5M/Sample

16 32
WES PE150 15Gb/Sample 1-2 2-4
Oncology targeted methylation panel PE150 ~5Gb/Sample 4 8

Small Genome Sequencing

Metagenomics for pathogen detection SE50, SE100 Meta: 20M/Sampple 4 8
Microbial WGS PE100, PE150 Single bacterium: ~1Gb/Sample 16-24 32-48

LOW pass whole-genome 






PGS SE35/ SE50

Transcriptome sequencing

RNA-Seq SE50, PE100, PE150

Expression profiling: ~1Gb/Sample

Transcriptome: ~8Gb/Sample



Cat. No Product Name
900-000607-00 DNBSEQ-G99RS
900-000609-00 DNBSEQ-G99ARS
940-000409-00 High-throughput Sequencing Set (G99 SM FCL SE100/PE50)
940-000410-00 High-throughput Sequencing Set (G99 SM FCL PE150)
940-000413-00 High-throughput Sequencing Set (G99 SM FCL APP-C PE150)
940-000624-00 DNBSEQ-G99RS Cleaning Reagent Kit
Selected as needed UPS

System Parameter

  • Product Model

    DNBSEQ-G99 (Without Bioinformatics Module)

    DNBSEQ-G99A (With Bioinformatics Module)

    DNBSEQ-G99RS (Without Bioinformatics Module)(1)

    DNBSEQ-G99ARS (With Bioinformatics Module)(1)

    (1) For research use only. Not for use in diagnostic procedures.

(1)Unless otherwise informed, StandardMPS and CoolMPS sequencing reagents, and sequencers for use with such reagents are not available in Germany, Spain, UK, Sweden, Belgium, Italy, Finland, Czech Republic, Switzerland, Portugal, Austria and Romania. Unless otherwise informed, StandardMPS sequencing reagents, and sequencers for use with such reagents are not available in Hong Kong.

  • Hotline (Global)
  • Email
  • Special Recommendations
  • *For research use only.

    Not for use in diagnostic procedures (except as specifically noted).
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