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CoolMPS™ and the non-coding Alzheimer's transcriptome: A 10-billion read puzzle
Release date:2019-12-17Writer:MGIViews:1789Share

Dr. Keller, who is doing research at Saarland and Stanford University is trying to understand how Alzheimer's and Parkinson's develop in the human body at small non coding RNA(sncRNA) level. Dr. Keller shows results of his research using alpha version of CoolMPS™ sequencing chemistry, where he finds CoolMPS™ provides a higher Q30 value -- the quality for each single base is much higher and the likelihood of wrong base calling is much lower in the new chemistry. High correlation has also been observed between the CoolMPS™ chemistry and existing data, which enables him to conduct quantitative analysis of new sncRNAs.

Dr. Andreas Keller
Dr. Andreas Keller
Department of Neurology and Neurological Sciences, Stanford University Chair for Clinical Bioinformatics, Saarland University

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